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We report a 70-year-old patient who presented with a 4-year history of weakness of paravertebral muscles.Electrodiagnostic studies revealed a mixed neurogenic-myopathic pattern.Light microscopic examination revealed atrophic fibers with rimmed vacuoles;electron microscopy demonstrated cytoplasmic and intranuclear filaments measuring about 16 nm in width, consistent with the diagnosis of inclusion body myositis.Therapy with corticosteroids provided only a mild and transient benefit.Ten months after the initial evaluation,clinical and electrodiagnostic examination demonstrated mild progression of the disease. |
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